Generic Avalide is a combination medication used to treat high blood pressure. One component belongs to a class of blood pressure medications that prevents the hormone angiotensin II from constricting the blood vessels, thereby allowing blood to flow more freely and keeping blood pressure down. The other component is a diuretic that increases the output of urine, removing excess fluid from the body and thus lowering blood pressure.
Entresto contains a combination of sacubitril and valsartan. Sacubitril is a blood pressure medicine. It works by increasing the levels of certain proteins in the body that can dilate (widen) blood vessels. This helps lower blood pressure by reducing sodium levels. Valsartan is an angiotensin II receptor blocker (sometimes called an ARB). Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. Entresto is used in certain people with chronic heart failure. This medicine helps lower the risk of needing to be hospitalized when symptoms get worse, and helps lower the risk of death from heart failure.
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